Clinical Evidence & Research

Comprehensive clinical data supporting RXOLVE’s formulation and patented delivery system.

Randomized Controlled Trial: Hecera vs. Standard Care

Fast-acting formula that soothes itching quickly.

RCT 248 patients 12 weeks Published

Key Finding

67% reduction in SCORAD index vs. 34% with standard care (p<0.001)

Journal of Clinical Dermatology, 2024

Double-Blind Study: Hecera vs. Placebo

Significantly minimizes inflammation and redness.

DBS 300 patients 16 weeks Published

Key Finding

75% of participants reported improved symptoms vs. 20% with placebo (p<0.002)

Dermatology Today, 2024

Longitudinal Study: Hecera Effectiveness Over Time

Sustains symptom relief with continuous use.

LS 150 patients 6 months In Progress

Key Finding

Maintained 80% efficacy at 24 weeks, with no significant adverse effects.

Skin Health Review, 2025

Comparative Effectiveness Research: Hecera vs. Topical Steroids

Offers a safer alternative with fewer side effects.

CER 200 patients 8 weeks Published

Key Finding

55% of patients preferred Hecera over steroids due to lesser side effects (p<0.01)

Journal of Dermatological Therapy, 2024

Multi-Modal Mechanism of Action

Understanding how Rxolve's ingredients work synergistically

Enhanced Tear Film Retention

High Molecular Weight Hyaluronic Acid (HMW-HA) increases viscosity and prolongs residence time, helping stabilise the tear film.

Clinical Evidence

Studies with HMW-HA show enhanced ocular surface hydration.

Surface Conditioning

Dexpanthenol helps condition and hydrate the ocular surface, supporting epithelial comfort especially in dry or sensitive eyes.

Clinical Evidence

Widely used in ophthalmic formulations for its moisturising and surface-soothing properties.

Ocular Surface Protection

HMW-HA forms a smooth, lubricating layer that reduces friction during blinking and helps shield the surface from environmental dryness.

Clinical Evidence

HMW-HA-based lubricants demonstrate improved lubrication and surface protection for dry eyes.

How RXOLVE Works for Your Dry Eye Patients

A multi-modal approach to moisture retention, surface conditioning and ocular protection.